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Affected erythrocytes of patients with paroxysmal nocturnal hemoglobinuria are deficient in the complement regulatory protein, decay accelerating factor.

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired defect of bone marrow stem cells in which the affected clones produce erythrocytes (also granulocytes and platelets) with membranes that are abnormally sensitive to complement-mediated lysis. Abnormal erythrocytes (E) from patients with PNH (P...

詳細記述

保存先:
書誌詳細
主要な著者: Nicholson-Weller, A, March, J P, Rosenfeld, S I, Austen, K F
フォーマット: Artigo
言語:Inglês
出版事項: 1983
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC384189/
https://ncbi.nlm.nih.gov/pubmed/6576376
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