Relationship between decay accelerating factor deficiency, diminished acetylcholinesterase activity, and defective terminal complement pathway restriction in paroxysmal nocturnal hemoglobinuria erythrocytes.

Paroxysmal nocturnal hemoglobinuria (PNH) erythrocytes exhibit abnormalities in decay accelerating factor (DAF), acetylcholinesterase, and resistance to autologous C5b-9 attack. To investigate the nature of the lesion underlying PNH cells, we examined the relationship of these abnormalities to one a...

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Détails bibliographiques
Auteurs principaux: Medof, M E, Gottlieb, A, Kinoshita, T, Hall, S, Silber, R, Nussenzweig, V, Rosse, W F
Format: Artigo
Langue:Inglês
Publié: 1987
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC442215/
https://ncbi.nlm.nih.gov/pubmed/2439544
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