Relationship between decay accelerating factor deficiency, diminished acetylcholinesterase activity, and defective terminal complement pathway restriction in paroxysmal nocturnal hemoglobinuria erythrocytes.

Paroxysmal nocturnal hemoglobinuria (PNH) erythrocytes exhibit abnormalities in decay accelerating factor (DAF), acetylcholinesterase, and resistance to autologous C5b-9 attack. To investigate the nature of the lesion underlying PNH cells, we examined the relationship of these abnormalities to one a...

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izdano v:	J Clin Invest
Principais autores:	Medof, M E, Gottlieb, A, Kinoshita, T, Hall, S, Silber, R, Nussenzweig, V, Rosse, W F
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 1987
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2439544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113043
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