Relationship between decay accelerating factor deficiency, diminished acetylcholinesterase activity, and defective terminal complement pathway restriction in paroxysmal nocturnal hemoglobinuria erythrocytes.

Paroxysmal nocturnal hemoglobinuria (PNH) erythrocytes exhibit abnormalities in decay accelerating factor (DAF), acetylcholinesterase, and resistance to autologous C5b-9 attack. To investigate the nature of the lesion underlying PNH cells, we examined the relationship of these abnormalities to one a...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Medof, M E, Gottlieb, A, Kinoshita, T, Hall, S, Silber, R, Nussenzweig, V, Rosse, W F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2439544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113043
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