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Respiratory Syncytial Virus Nonstructural Proteins Decrease Levels of Multiple Members of the Cellular Interferon Pathways

Viruses of the Paramyxoviridae family, such as the respiratory syncytial virus (RSV), suppress cellular innate immunity represented by type I interferon (IFN) for optimal growth in their hosts. The two unique nonstructural (NS) proteins, NS1 and NS2, of RSV suppress IFN synthesis, as well as IFN fun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Swedan, Samer, Musiyenko, Alla, Barik, Sailen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748017/
https://ncbi.nlm.nih.gov/pubmed/19625398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00715-09
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