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RNAi-dependent and -independent antiviral phenotypes of chromosomally integrated shRNA clones: Role of VASP in respiratory syncytial virus growth

Stable RNA interference (RNAi) is commonly achieved by recombinant expression of short hairpin RNA (shRNA). To generate virus-resistant cell lines, we cloned a shRNA cassette against the phosphoprotein gene of respiratory syncytial virus (RSV) into a polIII-driven plasmid vector. Analysis of individ...

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Autors principals: Musiyenko, Alla, Bitko, Vira, Barik, Sailen
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263383/
https://ncbi.nlm.nih.gov/pubmed/17351763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-007-0179-0
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