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Respiratory Syncytial Virus Nonstructural Proteins Decrease Levels of Multiple Members of the Cellular Interferon Pathways

Viruses of the Paramyxoviridae family, such as the respiratory syncytial virus (RSV), suppress cellular innate immunity represented by type I interferon (IFN) for optimal growth in their hosts. The two unique nonstructural (NS) proteins, NS1 and NS2, of RSV suppress IFN synthesis, as well as IFN fun...

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Autors principals: Swedan, Samer, Musiyenko, Alla, Barik, Sailen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748017/
https://ncbi.nlm.nih.gov/pubmed/19625398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00715-09
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