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Multiple Functional Domains and Complexes of the Two Nonstructural Proteins of Human Respiratory Syncytial Virus Contribute to Interferon Suppression and Cellular Location

Human respiratory syncytial virus (RSV), a major cause of severe respiratory diseases, efficiently suppresses cellular innate immunity, represented by type I interferon (IFN), using its two unique nonstructural proteins, NS1 and NS2. In a search for their mechanism, NS1 was previously shown to decre...

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Détails bibliographiques
Auteurs principaux: Swedan, Samer, Andrews, Joel, Majumdar, Tanmay, Musiyenko, Alla, Barik, Sailen
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196442/
https://ncbi.nlm.nih.gov/pubmed/21795342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00413-11
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