Cellular La Protein Shields Nonsegmented Negative-Strand RNA Viral Leader RNA from RIG-I and Enhances Virus Growth by Diverse Mechanisms

The La antigen (SS-B) associates with a wide variety of cellular and viral RNAs to affect gene expression in multiple systems. We show that La is the major cellular protein found to be associated with the abundant 44-nucleotide viral leader RNA (leRNA) early after infection with respiratory syncytia...

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Bibliographic Details
Main Authors: Bitko, Vira, Musiyenko, Alla, Bayfield, Mark A., Maraia, Richard J., Barik, Sailen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519562/
https://ncbi.nlm.nih.gov/pubmed/18550659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02762-07
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