Nonstructural Proteins of Respiratory Syncytial Virus Suppress Premature Apoptosis by an NF-κB-Dependent, Interferon-Independent Mechanism and Facilitate Virus Growth

The two nonstructural (NS) proteins NS1 and NS2 of respiratory syncytial virus (RSV) are abundantly expressed in the infected cell but are not packaged in mature progeny virions. We found that both proteins were expressed early in infection, whereas the infected cells underwent apoptosis much later....

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Detalhes bibliográficos
Main Authors: Bitko, Vira, Shulyayeva, Olena, Mazumder, Barsanjit, Musiyenko, Alla, Ramaswamy, Murali, Look, Dwight C., Barik, Sailen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797585/
https://ncbi.nlm.nih.gov/pubmed/17151097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01420-06
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