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Respiratory Syncytial Virus Nonstructural Proteins Decrease Levels of Multiple Members of the Cellular Interferon Pathways

Viruses of the Paramyxoviridae family, such as the respiratory syncytial virus (RSV), suppress cellular innate immunity represented by type I interferon (IFN) for optimal growth in their hosts. The two unique nonstructural (NS) proteins, NS1 and NS2, of RSV suppress IFN synthesis, as well as IFN fun...

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Detalhes bibliográficos
Main Authors: Swedan, Samer, Musiyenko, Alla, Barik, Sailen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748017/
https://ncbi.nlm.nih.gov/pubmed/19625398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00715-09
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