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Respiratory Syncytial Virus Nonstructural Proteins Decrease Levels of Multiple Members of the Cellular Interferon Pathways

Viruses of the Paramyxoviridae family, such as the respiratory syncytial virus (RSV), suppress cellular innate immunity represented by type I interferon (IFN) for optimal growth in their hosts. The two unique nonstructural (NS) proteins, NS1 and NS2, of RSV suppress IFN synthesis, as well as IFN fun...

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Autores principales: Swedan, Samer, Musiyenko, Alla, Barik, Sailen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748017/
https://ncbi.nlm.nih.gov/pubmed/19625398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00715-09
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