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Methoxycarbonyl-etomidate: A Novel Rapidly Metabolized and Ultra-Short Acting Etomidate Analogue That Does Not Produce Prolonged Adrenocortical Suppression

BACKGROUND: Etomidate is a rapidly-acting sedative-hypnotic that provides hemodynamic stability. However because it causes prolonged suppression of adrenocortical steroid synthesis, its clinical utility and safety are limited. We describe the results of studies to define the pharmacology of (R)-3-me...

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Bibliografski detalji
Glavni autori: Cotten, Joseph F., Husain, S. Shaukat, Forman, Stuart A., Miller, Keith W., Kelly, Elizabeth W., Nguyen, Hieu H., Raines, Douglas E.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739411/
https://ncbi.nlm.nih.gov/pubmed/19625798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181ae63d1
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