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microRNA-Mediated Messenger RNA Deadenylation Contributes to Translational Repression in Mammalian Cells
Animal microRNAs (miRNAs) typically regulate gene expression by binding to partially complementary target sites in the 3′ untranslated region (UTR) of messenger RNA (mRNA) reducing its translation and stability. They also commonly induce shortening of the mRNA 3′ poly(A) tail, which contributes to t...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728509/ https://ncbi.nlm.nih.gov/pubmed/19710908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006783 |
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