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Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system
MicroRNAs (miRNAs) are incorporated into miRNP complexes and regulate protein expression post-transcriptionally through binding to 3′-untranslated regions of target mRNAs. Here we describe a recapitulation of let-7 miRNA-mediated translational repression in a cell-free system, which was established...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1935024/ https://ncbi.nlm.nih.gov/pubmed/17671087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1566707 |
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