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PABP is not essential for microRNA-mediated translational repression and deadenylation in vitro
MicroRNAs silence their complementary target genes via formation of the RNA-induced silencing complex (RISC) that contains an Argonaute (Ago) protein at its core. It was previously proposed that GW182, an Ago-associating protein, directly binds to poly(A)-binding protein (PABP) and interferes with i...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2011
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3243625/ https://ncbi.nlm.nih.gov/pubmed/22117217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.426 |
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