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MicroRNAs direct rapid deadenylation of mRNA

MicroRNAs (miRNAs) are ubiquitous regulators of eukaryotic gene expression. In addition to repressing translation, miRNAs can down-regulate the concentration of mRNAs that contain elements to which they are imperfectly complementary. Using miR-125b and let-7 as representative miRNAs, we show that in...

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Detalhes bibliográficos
Main Authors: Wu, Ligang, Fan, Jihua, Belasco, Joel G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449641/
https://ncbi.nlm.nih.gov/pubmed/16495412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510928103
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