Načítá se...

Specificity of microRNA target selection in translational repression

MicroRNAs (miRNAs) are a class of noncoding RNAs found in organisms as evolutionarily distant as plants and mammals, yet most of the mRNAs they regulate are unknown. Here we show that the ability of an miRNA to translationally repress a target mRNA is largely dictated by the free energy of binding o...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Genes Dev
Hlavní autoři: Doench, John G., Sharp, Phillip A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC374233/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15014042/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1184404
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!