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mRNA isoform diversity can obscure detection of miRNA-mediated control of translation
Reporter-based studies support inhibition of translation at the level of initiation as a substantial component of the miRNA mechanism, yet recent global analyses have suggested that they predominantly act through decreasing target mRNA stability. Cells commonly coexpress several processing isoforms...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3096034/ https://ncbi.nlm.nih.gov/pubmed/21467217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2567611 |
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