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Probing the closed-loop model of mRNA translation in living cells

The mRNA closed-loop, formed through interactions between the cap structure, poly(A) tail, eIF4E, eIF4G and PAB, features centrally in models of eukaryotic translation initiation, although direct support for its existence in vivo is not well established. Here, we investigated the closed-loop using a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:RNA Biol
Main Authors: Archer, Stuart K, Shirokikh, Nikolay E, Hallwirth, Claus V, Beilharz, Traude H, Preiss, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615164/
https://ncbi.nlm.nih.gov/pubmed/25826658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1017242
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