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Probing the closed-loop model of mRNA translation in living cells

The mRNA closed-loop, formed through interactions between the cap structure, poly(A) tail, eIF4E, eIF4G and PAB, features centrally in models of eukaryotic translation initiation, although direct support for its existence in vivo is not well established. Here, we investigated the closed-loop using a...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Archer, Stuart K, Shirokikh, Nikolay E, Hallwirth, Claus V, Beilharz, Traude H, Preiss, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615164/
https://ncbi.nlm.nih.gov/pubmed/25826658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1017242
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