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Probing the closed-loop model of mRNA translation in living cells

The mRNA closed-loop, formed through interactions between the cap structure, poly(A) tail, eIF4E, eIF4G and PAB, features centrally in models of eukaryotic translation initiation, although direct support for its existence in vivo is not well established. Here, we investigated the closed-loop using a...

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Detalles Bibliográficos
Publicado en:RNA Biol
Autores principales: Archer, Stuart K, Shirokikh, Nikolay E, Hallwirth, Claus V, Beilharz, Traude H, Preiss, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615164/
https://ncbi.nlm.nih.gov/pubmed/25826658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1017242
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