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mRNA length-sensing in eukaryotic translation: reconsidering the “closed loop” and its implications for translational control

Most eukaryotic mRNAs are recruited to the ribosome by recognition of a 5’ m(7)GpppN cap. 30 years of genetic and biochemical evidence point to a role for interaction between the 5’ cap-interacting factors and the 3’ poly(A)-binding protein in bringing the ends of the mRNA into close proximity and p...

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Detalhes bibliográficos
Publicado no:Curr Genet
Main Authors: Thompson, Mary K., Gilbert, Wendy V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484751/
https://ncbi.nlm.nih.gov/pubmed/28028558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-016-0674-3
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