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mRNA length-sensing in eukaryotic translation: reconsidering the “closed loop” and its implications for translational control
Most eukaryotic mRNAs are recruited to the ribosome by recognition of a 5’ m(7)GpppN cap. 30 years of genetic and biochemical evidence point to a role for interaction between the 5’ cap-interacting factors and the 3’ poly(A)-binding protein in bringing the ends of the mRNA into close proximity and p...
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| Veröffentlicht in: | Curr Genet |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484751/ https://ncbi.nlm.nih.gov/pubmed/28028558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-016-0674-3 |
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