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Poly(A) leader of eukaryotic mRNA bypasses the dependence of translation on initiation factors

Eukaryotic mRNAs in which a poly(A) sequence precedes the initiation codon are known to exhibit a significantly enhanced cap-independent translation, both in vivo and in cell-free translation systems. Consistent with high expression levels of poxviral mRNAs, they contain poly(A) sequences at their 5...

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Detalhes bibliográficos
Main Authors: Shirokikh, Nikolay E., Spirin, Alexander S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2485544/
https://ncbi.nlm.nih.gov/pubmed/18658239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804940105
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