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Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes

The position of mRNA on 40S ribosomal subunits in eukaryotic initiation complexes was determined by UV crosslinking using mRNAs containing uniquely positioned 4-thiouridines. Crosslinking of mRNA positions (+)11 to ribosomal protein (rp) rpS2(S5p) and rpS3(S3p), and (+)9–(+)11 and (+)8–(+)9 to h18 a...

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Detalhes bibliográficos
Main Authors: Pisarev, Andrey V, Kolupaeva, Victoria G, Yusupov, Marat M, Hellen, Christopher UT, Pestova, Tatyana V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426728/
https://ncbi.nlm.nih.gov/pubmed/18464793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.90
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