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The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection

To elucidate an outline of the mechanism of eukaryotic translation initiation, 48S complex formation was analyzed on defined mRNAs in reactions reconstituted in vitro from fully purified translation components. We found that a ribosomal 40S subunit, eukaryotic initiation factor (eIF) 3, and the eIF2...

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Detalhes bibliográficos
Main Authors: Pestova, Tatyana V., Kolupaeva, Victoria G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187480/
https://ncbi.nlm.nih.gov/pubmed/12435632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1020902
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