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THE MECHANISM OF EUKARYOTIC TRANSLATION INITIATION AND PRINCIPLES OF ITS REGULATION

Protein synthesis is principally regulated at the initiation stage (rather than during elongation or termination), allowing rapid, reversible and spatial control over gene expression. Progress over recent years in determining the structures and activities of initiation factors, and in mapping their...

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Detalles Bibliográficos
Publicado en:Nat Rev Mol Cell Biol
Autores principales: Jackson, Richard J., Hellen, Christopher U.T., Pestova, Tatyana V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461372/
https://ncbi.nlm.nih.gov/pubmed/20094052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2838
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