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THE MECHANISM OF EUKARYOTIC TRANSLATION INITIATION AND PRINCIPLES OF ITS REGULATION

Protein synthesis is principally regulated at the initiation stage (rather than during elongation or termination), allowing rapid, reversible and spatial control over gene expression. Progress over recent years in determining the structures and activities of initiation factors, and in mapping their...

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Pubblicato in:Nat Rev Mol Cell Biol
Autori principali: Jackson, Richard J., Hellen, Christopher U.T., Pestova, Tatyana V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461372/
https://ncbi.nlm.nih.gov/pubmed/20094052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2838
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