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Stoichiometry and Change of the mRNA Closed-Loop Factors as Translating Ribosomes Transit from Initiation to Elongation

Protein synthesis is a highly efficient process and is under exacting control. Yet, the actual abundance of translation factors present in translating complexes and how these abundances change during the transit of a ribosome across an mRNA remains unknown. Using analytical ultracentrifugation with...

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Publicat a:PLoS One
Autors principals: Wang, Xin, Xi, Wen, Toomey, Shaun, Chiang, Yueh-Chin, Hasek, Jiri, Laue, Thomas M., Denis, Clyde L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783044/
https://ncbi.nlm.nih.gov/pubmed/26953568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150616
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