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Identification of a 57S translation complex containing closed-loop factors and the 60S ribosome subunit

In eukaryotic translation the 60S ribosome subunit has not been proposed to interact with mRNA or closed-loop factors eIF4E, eIF4G, and PAB1. Using analytical ultracentrifugation with fluorescent detection system, we have identified a 57S translation complex that contains the 60S ribosome, mRNA, and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Denis, Clyde L., Laue, Thomas M., Wang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068138/
https://ncbi.nlm.nih.gov/pubmed/30065356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29832-6
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