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Joining of 60S subunits and a translation-like cycle in 40S ribosome maturation

Assembly factors (AFs) prevent premature translation initiation on small (40S) ribosomal subunit assembly intermediates by blocking ligand binding. However, it is unclear how AFs are displaced from maturing 40S ribosomes, if or how maturing subunits are assessed for fidelity, and what prevents prema...

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Bibliografiske detaljer
Main Authors: Strunk, Bethany S., Novak, Megan N., Young, Crystal L., Karbstein, Katrin
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615461/
https://ncbi.nlm.nih.gov/pubmed/22770215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.04.044
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