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Translation elongation and mRNA stability are coupled through the ribosomal A-site

Messenger RNA (mRNA) degradation plays a critical role in regulating transcript levels in eukaryotic cells. Previous work by us and others has shown that codon identity exerts a powerful influence on mRNA stability. In Saccharomyces cerevisiae, studies using a handful of reporter mRNAs show that opt...

詳細記述

保存先:
書誌詳細
出版年:RNA
主要な著者: Hanson, Gavin, Alhusaini, Najwa, Morris, Nathan, Sweet, Thomas, Coller, Jeff
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140462/
https://ncbi.nlm.nih.gov/pubmed/29997263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.066787.118
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