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Translation elongation and mRNA stability are coupled through the ribosomal A-site
Messenger RNA (mRNA) degradation plays a critical role in regulating transcript levels in eukaryotic cells. Previous work by us and others has shown that codon identity exerts a powerful influence on mRNA stability. In Saccharomyces cerevisiae, studies using a handful of reporter mRNAs show that opt...
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| Veröffentlicht in: | RNA |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6140462/ https://ncbi.nlm.nih.gov/pubmed/29997263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.066787.118 |
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