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Codon optimality, bias and usage in translation and mRNA decay
The advent of ribosome profiling and other tools to probe mRNA translation has revealed that codon bias — the uneven use of synonymous codons in the transcriptome —serves as a secondary genetic code: a code that guides the efficiency of protein production, the fidelity of translation and the metabol...
Enregistré dans:
| Publié dans: | Nat Rev Mol Cell Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6594389/ https://ncbi.nlm.nih.gov/pubmed/29018283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm.2017.91 |
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