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Codon optimality, bias and usage in translation and mRNA decay

The advent of ribosome profiling and other tools to probe mRNA translation has revealed that codon bias — the uneven use of synonymous codons in the transcriptome —serves as a secondary genetic code: a code that guides the efficiency of protein production, the fidelity of translation and the metabol...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Rev Mol Cell Biol
Päätekijät: Hanson, Gavin, Coller, Jeff
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594389/
https://ncbi.nlm.nih.gov/pubmed/29018283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm.2017.91
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