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Attenuated Codon Optimality Contributes to Neural-Specific mRNA Decay in Drosophila

Tissue-specific mRNA stability is important for cell fate and physiology, but the mechanisms involved are not fully understood. We found that zygotic mRNA stability in Drosophila correlates with codon content: optimal codons are enriched in stable transcripts associated with metabolic functions like...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Burrow, Dana A., Martin, Sophic, Quail, Jade F., Alhusaini, Najwa, coller, Jeff, Cleary, Micheal D.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169788/
https://ncbi.nlm.nih.gov/pubmed/30110627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.039
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