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Structurally Simple, Potent, Plasmodium Selective Farnesyltransferase Inhibitors That Arrest the Growth of Malaria Parasites

Third world nations require immediate access to inexpensive therapeutics to counter the high mortality inflicted by malaria. Here, we report a new class of antimalarial protein farnesyltransferase (PFT) inhibitors, designed with specific emphasis on simple molecular architecture, to facilitate easy...

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Detaylı Bibliyografya
Asıl Yazarlar: Glenn, Matthew P., Chang, Sung-Youn, Hornéy, Carrie, Rivas, Kasey, Yokoyama, Kohei, Pusateri, Erin E., Fletcher, Steven, Cummings, Christopher G., Buckner, Frederick S., Pendyala, Prakash R., Chakrabarti, Debopam, Sebti, Saïd M., Gelb, Michael, Van Voorhis, Wesley C., Hamilton, Andrew D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728208/
https://ncbi.nlm.nih.gov/pubmed/16970397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm060081v
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