Defective domain–domain interactions within the ryanodine receptor as a critical cause of diastolic Ca(2+) leak in failing hearts

AIMS: A domain peptide (DP) matching the Gly(2460)–Pro(2495) region of the cardiac type-2 ryanodine receptor (RyR2), DPc10, is known to mimic channel dysfunction associated with catecholaminergic polymorphic ventricular tachycardia (CPVT), owing to its interference in a normal interaction of the N-t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tateishi, Hiroki, Yano, Masafumi, Mochizuki, Mamoru, Suetomi, Takeshi, Ono, Makoto, Xu, Xiaojuan, Uchinoumi, Hitoshi, Okuda, Shinichi, Oda, Tetsuro, Kobayashi, Shigeki, Yamamoto, Takeshi, Ikeda, Yasuhiro, Ohkusa, Tomoko, Ikemoto, Noriaki, Matsuzaki, Masunori
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721653/
https://ncbi.nlm.nih.gov/pubmed/18996969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvn303
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados