Survivin mediates aberrant hematopoietic progenitor cell proliferation and acute leukemia in mice induced by internal tandem duplication of Flt3

Internal tandem duplication mutations in the Flt3 tyrosine kinase gene (ITD-Flt3) and overexpression of Survivin are frequently found in patients with acute myeloid leukemia (AML). We investigated whether Survivin mediates the enhanced survival of primary hematopoietic progenitor cells (HPCs) result...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Fukuda, Seiji, Singh, Pratibha, Moh, Akira, Abe, Mariko, Conway, Edward M., Boswell, H. Scott, Yamaguchi, Seiji, Fu, Xin-Yuan, Pelus, Louis M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714213/
https://ncbi.nlm.nih.gov/pubmed/19411632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-11-188714
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars