載入...
Many different Vβ CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions
We have hypothesized that in the prenegative selection TCR repertoire, many somatically generated complementary-determining region (CDR) 3 loops combine with evolutionarily selected germline Vα/Vβ CDR1/CDR2 loops to create highly MHC/peptide cross-reactive T cells that are subsequently deleted by ne...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2009
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674405/ https://ncbi.nlm.nih.gov/pubmed/19416894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902728106 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|