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T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy
T cell-mediated allergy to Ni(++) is one of the most common forms of allergic contact dermatitis, but how the T-cell receptor (TCR) recognizes Ni(++) is unknown. We studied a TCR from an allergic patient that recognizes Ni(++) bound to the MHCII molecule DR52c containing an unknown self-peptide. We...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494899/ https://ncbi.nlm.nih.gov/pubmed/23091041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215928109 |
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