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Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules
The repertoire of αβ T cell antigen receptors (TCRs) on mature T cells is selected in the thymus where it is rendered both self-tolerant and restricted to the recognition of major histocompatibility complex molecules presenting peptide antigens (pMHC). It remains unclear whether germline TCR sequenc...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6825295/ https://ncbi.nlm.nih.gov/pubmed/31570608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909504116 |
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