Foreign Body Giant Cell Formation Is Preceded by Lamellipodia Formation and Can Be Attenuated by Inhibition of Rac1 Activation

Macrophages that are recruited to the site of implanted biomaterials undergo fusion to form surface-damaging foreign body giant cells. Exposure of peripheral blood monocytes to interleukin-4 can recapitulate the fusion process in vitro. In this study, we used interleukin-4 to induce multinucleation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jay, Steven M., Skokos, Eleni, Laiwalla, Farah, Krady, Marie-Marthe, Kyriakides, Themis R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934537/
https://ncbi.nlm.nih.gov/pubmed/17556592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061213
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados