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Rab5 Induces Rac-independent Lamellipodia Formation and Cell Migration

Rab5 is a regulatory GTPase of vesicle docking and fusion that is involved in receptor-mediated endocytosis and pinocytosis. Introduction of active Rab5 in cells stimulates the rate of endocytosis and vesicle fusion, resulting in the formation of large endocytic vesicles, whereas dominant negative R...

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Bibliografiske detaljer
Main Authors: Spaargaren, Marcel, Bos, Johannes L.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC25585/
https://ncbi.nlm.nih.gov/pubmed/10512863
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