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Loss of MCP-1 alters macrophage polarization and reduces NFκB activation in the foreign body response

Implantation of biomaterials elicits a foreign body response characterized by fusion of macrophages to form foreign body giant cells and fibrotic encapsulation. Studies of macrophage polarization in this response have suggested that alternative (M2) activation is associated with more favorable outco...

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Detalles Bibliográficos
Publicado en:Acta Biomater
Main Authors: Moore, Laura Beth, Sawyer, Andrew J., Charokopos, Antonios, Skokos, Eleni A., Kyriakides, Themis R.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278755/
https://ncbi.nlm.nih.gov/pubmed/25242651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2014.09.022
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