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Loss of MCP-1 alters macrophage polarization and reduces NFκB activation in the foreign body response

Implantation of biomaterials elicits a foreign body response characterized by fusion of macrophages to form foreign body giant cells and fibrotic encapsulation. Studies of macrophage polarization in this response have suggested that alternative (M2) activation is associated with more favorable outco...

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Detaylı Bibliyografya
Yayımlandı:Acta Biomater
Asıl Yazarlar: Moore, Laura Beth, Sawyer, Andrew J., Charokopos, Antonios, Skokos, Eleni A., Kyriakides, Themis R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278755/
https://ncbi.nlm.nih.gov/pubmed/25242651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2014.09.022
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