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Macrophage fusion leading to foreign body giant cell formation persists under phagocytic stimulation by microspheres in in vitro and in vivo in mouse models
The formation of surface-damaging foreign body giant cells (FBGC) from the fusion of macrophages is considered a hallmark of the foreign body response. Experimental evidence indicates that when macrophages are unable to internalize foreign bodies via phagocytosis due to their large size, they acquir...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826601/ https://ncbi.nlm.nih.gov/pubmed/19536825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.32513 |
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