Macrophage fusion, giant cell formation, and the foreign body response require matrix metalloproteinase 9

Macrophages undergo fusion to form multinucleated giant cells in several pathologic conditions, including the foreign body response (FBR). We detected high levels of matrix metalloproteinase (MMP)-9 during macrophage fusion in vitro and in foreign body giant cells (FBGCs) in vivo. Wild-type (WT) bon...

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Detalhes bibliográficos
Main Authors: MacLauchlan, Susan, Skokos, Eleni A., Meznarich, Norman, Zhu, Dana H., Raoof, Sana, Shipley, J. Michael, Senior, Robert M., Bornstein, Paul, Kyriakides, Themis R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2009
Assuntos:
Cell Development, Growth, Differentiation, and Trafficking
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656428/
https://ncbi.nlm.nih.gov/pubmed/19141565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1008588
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