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Thrombospondin-2 Modulates Extracellular Matrix Remodeling during Physiological Angiogenesis

Thrombospondin 2 (TSP2) can inhibit angiogenesis in vitro by limiting proliferation and inducing apoptosis of endothelial cells (ECs). TSP2 can also modulate the extracellular levels of gelatinases (matrix metalloproteases, MMPs) and potentially influence the remodeling of the extracellular matrix (...

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Bibliografiska uppgifter
Huvudupphovsmän: Krady, Marie M., Zeng, Jianmin, Yu, Jun, MacLauchlan, Susan, Skokos, Eleni A., Tian, Weiming, Bornstein, Paul, Sessa, William C., Kyriakides, Themis R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527070/
https://ncbi.nlm.nih.gov/pubmed/18688033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080128
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