Thrombospondin-2 Modulates Extracellular Matrix Remodeling during Physiological Angiogenesis

Thrombospondin 2 (TSP2) can inhibit angiogenesis in vitro by limiting proliferation and inducing apoptosis of endothelial cells (ECs). TSP2 can also modulate the extracellular levels of gelatinases (matrix metalloproteases, MMPs) and potentially influence the remodeling of the extracellular matrix (...

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Detalhes bibliográficos
Main Authors: Krady, Marie M., Zeng, Jianmin, Yu, Jun, MacLauchlan, Susan, Skokos, Eleni A., Tian, Weiming, Bornstein, Paul, Sessa, William C., Kyriakides, Themis R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527070/
https://ncbi.nlm.nih.gov/pubmed/18688033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080128
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