Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2

Injury- and ischemia-induced angiogenesis is critical for tissue repair and requires nitric oxide (NO) derived from endothelial nitric oxide synthase (eNOS). We present evidence that NO induces angiogenesis by modulating the level of the angiogenesis inhibitor thrombospondin 2 (TSP2). TSP2 levels we...

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Hauptverfasser: MacLauchlan, Susan, Yu, Jun, Parrish, Marcus, Asoulin, Tara A., Schleicher, Michael, Krady, Marie M., Zeng, Jianmin, Huang, Paul L., Sessa, William C., Kyriakides, Themis R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219156/
https://ncbi.nlm.nih.gov/pubmed/21949402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104357108
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