Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2

Injury- and ischemia-induced angiogenesis is critical for tissue repair and requires nitric oxide (NO) derived from endothelial nitric oxide synthase (eNOS). We present evidence that NO induces angiogenesis by modulating the level of the angiogenesis inhibitor thrombospondin 2 (TSP2). TSP2 levels we...

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Bibliographic Details
Main Authors: MacLauchlan, Susan, Yu, Jun, Parrish, Marcus, Asoulin, Tara A., Schleicher, Michael, Krady, Marie M., Zeng, Jianmin, Huang, Paul L., Sessa, William C., Kyriakides, Themis R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219156/
https://ncbi.nlm.nih.gov/pubmed/21949402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104357108
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