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Morphine Induces Desensitization of Insulin Receptor Signaling

Morphine analgesia is mediated principally by the μ-opioid receptor (MOR). Since morphine and other opiates have been shown to influence glucose homeostasis, we investigated the hypothesis of direct cross talk between the MOR and the insulin receptor (IR) signaling cascades. We show that prolonged m...

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Li, Yu, Eitan, Shoshana, Wu, Jiong, Evans, Christopher J., Kieffer, Brigitte, Sun, Xiaojian, Polakiewicz, Roberto D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180943/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12917346/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.17.6255-6266.2003
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