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Morphine Induces Desensitization of Insulin Receptor Signaling

Morphine analgesia is mediated principally by the μ-opioid receptor (MOR). Since morphine and other opiates have been shown to influence glucose homeostasis, we investigated the hypothesis of direct cross talk between the MOR and the insulin receptor (IR) signaling cascades. We show that prolonged m...

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Publicado no:Mol Cell Biol
Principais autores: Li, Yu, Eitan, Shoshana, Wu, Jiong, Evans, Christopher J., Kieffer, Brigitte, Sun, Xiaojian, Polakiewicz, Roberto D.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180943/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12917346/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.17.6255-6266.2003
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